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Chronic kidney failure is a bit different than acute kidney failure: it develops slowly over a period of weeks, months or years in some patients with kidney disease

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3. Swelling

Fluid buildup in the face, hands, and feet leads (known as edema) may mean that the kidneys are not getting rid of waste at an appropriate rate, and so your body is beginning to store it in other tissues. In some cases, patients find that they’re losing weight throughout their body, but their face and eyes are noticeably puffy. In other cases, ankles become so swollen that it’s difficult to walk comfortably.

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